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Introduction Plant pathogenic fungi are major pathogens
2024-05-16
Introduction Plant pathogenic fungi are major pathogens in agricultural diseases and the cause of large crop losses worldwide. There are many kinds of plant pathogenic fungi, with various modes of action. For example, Botrytis cinerea (B. cinerea) is the disease pathogen in the economically importa
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br Natriuretic peptides and neprilysin Left ventricular syst
2024-05-16
Natriuretic peptides and neprilysin Left ventricular systolic function, most commonly due to myocardial damage as a consequence of coronary artery disease, hypertension or both, and leading to sustained, pathological activation of the renin angiotensin influenza m2 protein system (RAAS) and symp
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Moreover a multiple regression analysis
2024-05-16
Moreover, a multiple regression analysis using the 1-year MMSE score as a dependent variable was conducted. The result showed that serum Leupeptin australia levels at admission did not affect the MMSE score 1 year later (β = 0.10, p = 0.639). Discussion In this study, serum Aβ42 levels were sig
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Recently rather than predicting categorical variables as in
2024-05-16
Recently, rather than predicting categorical variables as in classification, several studies begin to estimate continuous clinical variables from EPZ004777 receptor images. Therefore, instead of classify a subject into binary or multiple pre-determined categories or stages of the disease, regressio
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This study revealed that EAAT expression was
2024-05-16
This study revealed that EAAT2 bosentan was increased 4–8 weeks after cauterization as our previous work (Park et al., 2009). RGC death could not be blocked despite activation of EAAT2, which is one of glutamate transporters in cone photoreceptors and some bipolar cells, in chronic ocular hypertensi
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Implicit in this concept is the
2024-05-16
Implicit in this concept is the idea that the β-adrenoceptors in the detrusor would be activated by adrenergic nerves of the sympathetic system: sympathetic activity promoting relaxation and enhancing bladder capacity. However, it has been demonstrated that there is only a sparse adrenergic innervat
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Encouraged by this observation a
2024-05-15
Encouraged by this observation, a systematic SAR study on the A ring -alkoxy was conducted as summarized in . The A ring methoxy-containing KRCA-0008 was proven an optimal substituent in terms of potency after all and its bigger size derivatives were detrimental in both biochemical and H3122 cellula
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br Acknowledgement br Introduction There
2024-05-15
Acknowledgement Introduction There has been great progress in the treatment of autoimmune disease during the past several decades. However, the majority of autoimmune diseases have no known cure. B lymphocytes and autoantibodies play important roles in many autoimmune diseases, including rheum
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If the lack of specificity and
2024-05-15
If the lack of specificity and the high pleiotropy may represent a problem in view of the potential chemotherapeutic features of autophagy-inducing agents, it Y-27632 may switch into an advantage in the case of chemopreventive strategies. In fact, as non-pharmacologic interventions such as limited
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BIBR 1532 Elevated expression of Aurora A
2024-05-15
Elevated expression of Aurora-A and -B frequently detected in a wide variety of human cancers strongly indicate that high expression of these kinases play roles in the development of cancer associated phenotypes. While Aurora-A has been shown to function as an oncogene when over expressed in mammali
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Congruously our findings of voltage electrode clamping assay
2024-05-15
Congruously, our findings of voltage-electrode-clamping assays indicate that hipN851K mutation mediates partial loss of Na+/K+-ATPase pump currents, also confirming our thesis that hipN851K mutation acts as a hypomorph. As demonstrated here by our external electrical stimulation studies and ECG reco
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Here we investigate the ATM to ATR
2024-05-15
Here, we investigate the ATM to ATR switch in normal human fibroblasts (82-6 cells) after irradiation with γ-rays, or high LET 56Fe and 28Si and moderate LET 16O particles. Our data provide important evidence of LET dependence on the transition of ATM to ATR as well as end resection at the sites of
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There are in contrast many studies demonstrating that
2024-05-15
There are in contrast many studies demonstrating that sex steroids modulate labetalol hydrochloride processing of stimuli related to reproduction and this correlates with the observation that steroid receptors and aromatase are expressed in many brain nuclei that are part of the olfactory, visual a
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br Materials and Methods br Results br
2024-05-15
Materials and Methods Results Discussion XHP is a traditional Chinese anti-cancer medicine that is widely used for the treatment and adjuvant treatment of breast cancer. XHP has been shown to induce apoptosis in various breast cancer Methylprednisolone Sodium Succinate in vitro, including H
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br Nanoparticle Conjugated Topoisomerase Inhibitors The
2024-05-15
Nanoparticle-Conjugated Topoisomerase Inhibitors The safety and efficacy of topotecan administered as LDM or MTD have been evaluated in several preclinical studies and a few clinical trials whose results showed that there can be significant adverse effects likely precluding its use in patients [5
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