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Our results implicate a critical role for CXCR in promoting
2019-09-24
Our results implicate a critical role for CXCR-1 in promoting the migration of colonic tumor cells. Expression of this receptor, but not CXCR-2, increased significantly because of the EMT (Fig. 3). Moreover, although Clone A brucine express comparable levels of both IL-8 receptors, only CXCR-1 inhi
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br Bipartite graph br Algorithm for
2019-09-24
Bipartite graph Algorithm for CFC Error detection rate and overhead evaluation Test results and discussion For verifying the proof in Hydroxyurea kinase from the perspective of practice, this section brings tests and analysis based on the onboard computer (OBC) of the in-service ZDPS-1A
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On top of the hardware ASTS employs Linux SUSE
2019-09-24
On top of the hardware, ASTS employs Linux SUSE with High-Availability (HA) Extension: a COTS OS provided with two clustering software (Pacemaker Cluster Resource Manager (CRM) and Corosync) responsible for resources orchestration, failure diagnosis, nodes coordination, and fail-over management. The
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As the COMT enzyme is primarily related to prefrontal
2019-09-24
As the COMT enzyme is primarily related to prefrontal dopamine degradation (e.g., Yavich et al., 2007), the present study supports the notion that prefrontal dopamine modulates retention of fear extinction rather than within-session extinction (Abraham et al., 2014). Consistent with other studies we
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br Progestogens and venous thromboembolism clinical data br
2019-09-24
Progestogens and venous thromboembolism: clinical data Progestogens and haemostatis: biological studies For many years, the effect of HT on haemostatis has been largely investigated in observational studies as well as in high evidence level studies among users of oral and transdermal estrogens
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br Discussion EFTs are sarcomas with almost undifferentiated
2019-09-24
Discussion EFTs are sarcomas with almost undifferentiated histologic features, consequently their differentiation from other small, blue, round cell tumors may be difficult. Substantial intracellular 4E1RCat clinical on PAS stain is a useful diagnostic feature. The addition of CD99 and FLI1 immu
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Our results are the first to
2019-09-24
Our results are the first to demonstrate that ERRγ acts as a catabolic regulator of cartilage degeneration and OA pathogenesis, and collectively support the idea that ERRγ could be a therapeutic target for OA Introduction DNA cytosine-5-methyltransferases (Dnmts) catalyze the methyl transfer fr
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br Conclusions br Declaration of
2019-09-24
Conclusions Declaration of interest Acknowledgements Introduction Uncorrected obesity has been a major health problem and the prevalence of obesity is fast rising reaching an epidemic proportion [[1], [2], [3]]. Ample of clinical and experimental evidence has suggested that obesity leads
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To get an indication whether GBM derived OHC
2019-09-24
To get an indication whether GBM-derived 25-OHC could act as a chemotactic signal for monocytes, lipid extracts of GM133 media were used in THP-1 migration assays. Although an indirect approach, these experiments revealed that medium lipid extracts induced monocyte migration in a quantitatively comp
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Western blotting and flow cytometry was employed to assess
2019-09-24
Western blotting and flow cytometry was employed to assess the DNA-PK inhibition of LTU28 and LTU31 in combination with radiation. It has been previously reported that phosphorylation of DNA-PKcs at the Thr2609 cluster plays an important role in DSB repair and resistance to radiation (Ding et al., 2
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Structural homology modelling Intensive Phyre modelling was
2019-09-24
Structural homology modelling. Intensive Phyre2 modelling [44] was performed using the primary amino pmsf molecular weight sequence of A1S_0222 as input to generate an atomistic 3D-homology model of A1S_0222. The fit to the SAXS data of the homology model as well as the fit to the data of the E. co
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Kluveromyces lactisSimilar to S cerevisiae K lactis is
2019-09-24
Kluveromyces lactisSimilar to S. cerevisiae, K. lactis is a facultative anaerobic respiratory yeast, which lacks Complex I in its mitochondrial respiratory chain. However, both yeasts differ regarding their respiratory-fermentative metabolism as K. lactis exhibits a greater use of the pentose phosph
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Sodium Picosulfate clinical br Experimental br Results and
2019-09-24
Experimental Results and discussion Conclusions In this work we presented the direct electrochemical behaviour of the Mo containing formate dehydrogenase, purified from D. desulfuricans, where the Mo centre redox features were observed. The results allowed to calculate the reduction potenti
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Global inhibition of integrin signaling with EDTA here sugge
2019-09-24
Global inhibition of integrin signaling with EDTA here suggests that integrin signaling potentially cooperates with DDR2 in collagen induction of lysyl oxidase. This notion is supported by a recent study that shows DDR2 cooperation with specific integrins in cell adhesion to collagen [47]. It is of
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br Crystal structure of c FMS and binding pattern
2019-09-23
Crystal structure of c-FMS and binding pattern of CSF-1 and IL-34 c-FMS is a 972 amino acids polypeptides containing transmembrane glycoprotein [19]. It contains all the necessary domains required for tyrosine kinase activity, i.e. 512 amino 12-O-tetradecanoyl phorbol-13-acetate N-terminal extra
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